ΠΡΠΈΡΡΠΎΡ ΠΠΎΡ ΡΠΈΡΠΈΡΡΠ΅Ρ ΠΏΡΠ΅ΡΡ Π’Π΅Π½Π½Π΅ΡΡΠΈ Π£ΠΈΠ»ΡΡΠΌΡΠ° "ΠΠΎΠ»ΠΎΡΠ½ΡΠΉ ΡΡΡΠ³ΠΎΠ½ Π·Π΄Π΅ΡΡ Π±ΠΎΠ»ΡΡΠ΅ Π½Π΅ ΠΎΡΡΠ°Π½Π°Π²Π»ΠΈΠ²Π°Π΅ΡΡΡβ Π½Π° ΡΡΡ. 187 ΠΊΠ½ΠΈΠ³ΠΈ: Π‘. ΠΠΎΠ΅Π½, The Quest for Consciousness: A Neurobiological Approach (Englewood, Col.: Roberts, 2004).
ΠΠ»Π΅ΡΠΊΠΈ ΠΌΠ΅ΡΡΠ° Π±ΡΠ»ΠΈ Π²ΠΏΠ΅ΡΠ²ΡΠ΅ ΠΎΠΏΠΈΡΠ°Π½Ρ Π² ΡΡΠ°ΡΡΠ΅: J. OβKeefe & J. D Ostrovsky. The hippocampus as a spatial ΡΠ°Ρ. Preliminary evidence from unit activity in the freely-moving rat. Brain Res. 34, no. 1 (1971): 171β175.
ΠΡΠ΅ΠΊΡΠ°ΡΠ½ΡΠΉ ΠΎΠ±Π·ΠΎΡ Π΄ΠΎΠ»Π³ΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠΉ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°ΡΠΈΠΈ ΠΌΠΎΠΆΠ½ΠΎ Π½Π°ΠΉΡΠΈ Π² ΠΊΠ½ΠΈΠ³Π΅: Π’. Bliss, G. Collingridge & R. Morris, eds., LTP: Long-Term Potentiation (Oxford: Oxford University Press, 2003). Π ΡΡΠΎΠΌ ΡΠ±ΠΎΡΠ½ΠΈΠΊΠ΅ ΠΎΠΏΡΠ±Π»ΠΈΠΊΠΎΠ²Π°Π½ΠΎ Π½Π΅ΠΌΠ°Π»ΠΎ ΠΏΠΎΠ»Π΅Π·Π½ΡΡ ΡΡΠ°ΡΠ΅ΠΉ, Π² ΡΠ°ΡΡΠ½ΠΎΡΡΠΈ ΡΠ»Π΅Π΄ΡΡΡΠΈΠ΅: P. Andersen, A prelude to long-term potentiation; R. Malinow, AMPA receptor trafficking and long-term potentiation; R. G. M. Morris, Longterm potentiation and memory; R. A. Nicoll, Expression mechanisms underlying long-term potentiation: a postsynaptic view.
ΠΡΡΠ³ΠΈΠ΅ ΡΠ²Π΅Π΄Π΅Π½ΠΈΡ, ΠΏΡΠΈΠ²Π΅Π΄Π΅Π½Π½ΡΠ΅ Π² ΡΡΠΎΠΉ Π³Π»Π°Π²Π΅, ΠΏΠΎΡΠ΅ΡΠΏΠ½ΡΡΡ ΠΈΠ· ΡΠ»Π΅Π΄ΡΡΡΠΈΡ ΠΈΡΡΠΎΡΠ½ΠΈΠΊΠΎΠ²:
Baudry, Π., R. Siman, Π. Π. Smith & G. Lynch. Regulation by calcium ions of glutamate receptor binding in hippocampal slices. Euro. J. Pharmacol. 90, no. 2β3 (1983): 161β168.
Bliss, Π’. V. & T. Lamo. Long-lasting potentiation of synaptic transmission in the dentate gyrus of the anesthethized rabbit following stimulation oftheperforantpath. J. Physiol. 232 (1973): 331β356.
Collingridge, G. L., S. J. Kehl 81 H. McLennan. Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampus. J. Physiol. (London) 334 (1983): 33β46.
Curtis, D. R., j. W. Phillis & J. C. Watkins. The chemical excitation of spinal neurons by certain acidic amino acids. J. Physiol. 150 (1960): 656β682.
Eccles J. C. The Physiology of Synapses. Berlin: Springer Verlag, 1964.
Hebb, D. 0. The Organization of Behavior: A Neuropsychological Theory. New York: Wiley, 1949; ΠΏΡΠΈΠ²Π΅Π΄Π΅Π½Π½Π°Ρ ΡΠΈΡΠ°ΡΠ° β ΡΡΡ. 62.
Nowak, L., P. Bregestovski, P. Ascher, A. Herbet & A. Prochiantz. Magnesium gates glutamate-activated channels in mouse central neurons. Nature 307 (1984): 462β465.
OβDell, T. J., S. G. N. Grant, K. Karl, P. M. Soriano & E. R. Kandel. Pharmacological and genetic approaches to the analysis of tyrosine kinase function in long-term potentiation. Cold Spring Harbor Symp. Quant. Biol. 57 (1992): 517β526.
Roberts, P. J. &. J. C. Watkins. Structural requirements for inhibition for L-glutamate uptake by glia and nerve endings. Brain Res. 85, no. 1 (1975): 120β125.
Schacter, D. L. Searching for Memory: The Brain, the Mind and the Past. New York: Basic Books, 1996.
Spencer, W. A. & E. R. Kandel. Electrophysiology of hippocampal neurons. IV: Fast prepotentials. J. Neurophysiol. 24 (1961): 272β285. Westbrook, G. L. & M. L. Mayer. Glutamate currents in mammalian spinal neurons resolution of a paradox. Brain Res. 301, no. 2 (1984): 375β379.
21. Π‘ΠΈΠ½Π°ΠΏΡΡ Ρ ΡΠ°Π½ΡΡ ΠΈ Π½Π°ΡΠΈ ΡΠ°ΠΌΡΠ΅ ΡΠ΅ΠΏΠ»ΡΠ΅ Π²ΠΎΡΠΏΠΎΠΌΠΈΠ½Π°Π½ΠΈΡ
ΠΠ΅ΡΠΎΠ΄Ρ ΠΏΠΎΠ»ΡΡΠ΅Π½ΠΈΡ Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΈ ΠΌΠΎΠ΄ΠΈΡΠΈΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ ΠΌΡΡΠ΅ΠΉ ΠΎΠΏΠΈΡΠ°Π½Ρ Π² ΡΡΠ°ΡΡΡΡ : R. L. Brinster & R. D. Palmiter. Induction of foreign genes in animals. Trends Biochem. Sri. 7 (1982): 438β440 ΠΈ M. R. Capecchi, High-efficiency transformation by direct microinjection ofDNA into cultured mammalian cells. Cell 22, no. 2 (1980): 479β488.
ΠΠ΅ΡΠ²ΡΠ΅ Π΄Π°Π½Π½ΡΠ΅ ΠΎΠ± ΡΡΡΠ΅ΠΊΡΠ΅ Π½ΠΎΠΊΠ°ΡΡΠ° Π³Π΅Π½ΠΎΠ² Π½Π° Π΄ΠΎΠ»Π³ΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°ΡΠΈΡ ΠΈ ΠΏΡΠΎΡΡΡΠ°Π½ΡΡΠ²Π΅Π½Π½ΡΡ ΠΏΠ°ΠΌΡΡΡ Π±ΡΠ»ΠΈ ΠΎΠΏΡΠ±Π»ΠΈΠΊΠΎΠ²Π°Π½Ρ Π² ΡΡΠ°ΡΡΡΡ : S. G. N. Grant, Π’. J. OβDell, Π. A. Karl, P. L. Stein, P. Soriano & E. R. Kandel, Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice. Science 258 (1992): 1903β1910; A. J. Silva, R. Paylor, J. M. Wehner & S. Tonegawa, Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice. Science 257 (1992): 206β211.
ΠΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΡ Ρ ΡΡΠ°ΡΡΠΈΠ΅ΠΌ Π‘ΡΠΈΠ²Π΅Π½Π° ΠΠΈΠ³Π΅Π»ΡΠ±Π°ΡΠΌΠ°, ΡΠΏΠΎΠΌΠΈΠ½Π°Π΅ΠΌΡΠ΅ ΡΠ°ΠΊΠΆΠ΅ Π² Π³Π»Π°Π²Π΅ 9, Π²ΠΌΠ΅ΡΡΠ΅ Ρ Π½ΠΈΠΌ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ ΠΡΡΡ ΠΠΎΠ»Π°Π½ ΠΈ ΠΠΆΠΎΡ ΠΠ°Π΄ΠΌΠ°Π½. ΠΡΠΈ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΡ ΠΎΠΏΠΈΡΠ°Π½Ρ Π² ΡΡΠ°ΡΡΡΡ : Π. F. Nolan, G. Malleret, J. Π’. Dudman, D. Buhl, Π. Santoro, Π. Gibbs, S. Vronskaya, G. Buzsaki, S. A. Siegelbaum, E. R. Kandel & A. Morozov, A behavioral role for dendritic integration: HCNi channels constrain spatial memory and plasticity at inputs to distal dendrites of CAi pyramidal neurons. Cell 119 (2004): 719β732.
ΠΡΡΠ³ΠΈΠ΅ ΡΠ²Π΅Π΄Π΅Π½ΠΈΡ, ΠΏΡΠΈΠ²Π΅Π΄Π΅Π½Π½ΡΠ΅ Π² ΡΡΠΎΠΉ Π³Π»Π°Π²Π΅, ΠΏΠΎΡΠ΅ΡΠΏΠ½ΡΡΡ ΠΈΠ· ΡΠ»Π΅Π΄ΡΡΡΠΈΡ ΠΈΡΡΠΎΡΠ½ΠΈΠΊΠΎΠ²:
Mayford, Π., Π’. Abel & E. R. Kandel. Transgenic approaches to cognition. Curr. Opin. Neurobiol. 5 (1995): 141β148.
Mayford, Π., Π. E. Bach, Y. Y. Huang, L. Wang, R. D. Hawkins & E. R. Kandel. Control of memory formation through regulated expression of a CaMUIa transgene. Science 274 (1996): 1678β1683.
Mayford, Π., D. Baranes, K. Podyspanina & E. R. Kandel. The 3' β untranslated region of CaMUIa is a cis-acting signal for the localization and translation ofmRNA in dendrites. Proc. Natl. Acad. Sri. USA 93 (1996): 13 250-13255.
Silva, A. J., C. F. Stevens, S. Tonegawa & Y. Wang. Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinaseII mutant mice. Science 257 (1992): 201β206.
Tsien, J. Z., D. F. Chen, D. Gerber, C. Tom, E. H. Mercer, D. J. Anderson, M. Mayford, E. R. Kandel & S. Tonegawa. Subregion and cell-type restricted gene knockout in mouse brain. Cell 87 (1996): 1317β1326.
Tsien, J. Z., P. T. Huerta & S. Tonegawa. The essential role of hippocampal CAi NMDA receptor-dependent synaptic plasticity in spatial memory. Cell 87 (1996): 1327β1338.
22. ΠΠΎΠ·Π³ ΠΈ Π΅Π³ΠΎ ΠΊΠ°ΡΡΠΈΠ½Π° ΠΎΠΊΡΡΠΆΠ°ΡΡΠ΅Π³ΠΎ ΠΌΠΈΡΠ°
Π ΠΊΠΎΠ³Π½ΠΈΡΠΈΠ²Π½ΡΡ ΡΡΠ½ΠΊΡΠΈΡΡ Ρ ΡΠΎΡΠΊΠΈ Π·ΡΠ΅Π½ΠΈΡ Π½Π΅Π²ΡΠΎΠ»ΠΎΠ³Π° ΡΠΌ.: S. Freud, The Interpretation of Dreams, 1900 (reprint, London: Hogarth, 1953) ΠΈ Π. Sacks, The Man Who Mistook His Wife for a Hat (New York: Alfred A. Knopf, 1985).
Π ΠΊΠΎΠ³Π½ΠΈΡΠΈΠ²Π½ΠΎΠΉ ΠΏΡΠΈΡ ΠΎΠ»ΠΎΠ³ΠΈΠΈ ΡΠΌ.: G. A. Miller, Psychology: The Science of Mental Life (New York: Harper & Row, 1962) ΠΈ U. Neisser, Cognitive Psychology (New York: Appleton-Century-Crofts, 1967), ΠΏΡΠΈΠ²Π΅Π΄Π΅Π½Π½Π°Ρ ΡΠΈΡΠ°ΡΠ° β Π°Ρ. 3.
Π ΡΠ°Π±ΠΎΡΠ°Ρ ΠΠ°ΡΠ½ΡΠΊΠ°ΡΠ»Π°, Π₯ΡΡΠ±Π΅Π»Π° ΠΈ ΠΠΈΠ·Π΅Π»Π° ΡΠΌ.: D. Π. Hubel & Π’. N. Wiesel, Brain and Visual Perception (New York: Oxford University Press, 2005); V. B. Mountcastle, Central nervous mechanisms in mechanoreceptive sensibility, in: Handbook of Physiology. Section 1, The Nervous System. Vol. 3, Sensory Processes, Part 2, 789β878, ed.
I. Darian Smith (Bethesda, Md.: American Physiological Society, 1984); V. B. Mountcastle, The view from within: Pathways to the study of perception, Johns Hopkins Med. J. 136, no. 3 (1975): 109β131, ΠΏΡΠΈΠ²Π΅Π΄Π΅Π½Π½Π°Ρ ΡΠΈΡΠ°ΡΠ° β ΡΡΡ. 109 (ΠΊΡΡΡΠΈΠ² Π°Π²ΡΠΎΡΠ°).
ΠΡΡΠ³ΠΈΠ΅ ΡΠ²Π΅Π΄Π΅Π½ΠΈΡ, ΠΏΡΠΈΠ²Π΅Π΄Π΅Π½Π½ΡΠ΅ Π² ΡΡΠΎΠΉ Π³Π»Π°Π²Π΅, ΠΏΠΎΡΠ΅ΡΠΏΠ½ΡΡΡ ΠΈΠ· ΡΠ»Π΅Π΄ΡΡΡΠΈΡ ΠΈΡΡΠΎΡΠ½ΠΈΠΊΠΎΠ²:
Evarts, Π. V. Pyramidal tract activity associated with a conditioned hand movement in the monkey. J. Neurophysiol. 29 (1966): 1011β1027.
Gregory, R. L. ed. The Oxford Companion to the Mind. Oxford: Oxford University Press, 1987.
Marshall, W. H., C. N. Woolsey 81 P. Bard. Observations on cortical somatic sensory mechanisms of cat and monkey.]. Neurophysiol. 4 (1941): 1β24.
Marshall, W. H. & S. A. Talbot. Recent evidence for neural mechanisms in vision leading to a general theory of sensory acuity. In: Visual Mechanisms, ed. H. Kluver, 117β164. Lancaster, Pa.: Cattell, 1942.
Movshon, J. A. Visual processing of moving images. In: Images and Understanding: Thoughts About Images; Ideas About Understanding, ed. H. Barlow, C. Blakemore & M. Weston β Smith, 122β137. New York: Cambridge University Press, 1990.
Tolman, E. C. Purposive Behavior in Animals and Men. New York: Century, 1932.
Wurtz, R. H., Π. E. Goldberg, and D. L. Robinson. Brain mechanisms of visual attention. Sci. Am. 246, no. 6 (1982): 124.
Zeki, S. M. A Vision of the Brain. Oxford: Oxford University Press, 1993; ΠΏΡΠΈΠ²Π΅Π΄Π΅Π½Π½Π°Ρ ΡΠΈΡΠ°ΡΠ° β ΡΡΡ. 295β296 (ΠΊΡΡΡΠΈΠ² Π°Π²ΡΠΎΡΠ°).
23. ΠΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΡ Π²Π½ΠΈΠΌΠ°Π½ΠΈΡ
ΠΠΎΠ΄ΡΠΎΠ±Π½ΠΎΡΡΠΈ ΠΎ Π³ΠΈΠΏΠΏΠΎΠΊΠ°ΠΌΠΏΠ΅ ΠΈ Π²ΠΎΡΠΏΡΠΈΡΡΠΈΠΈ ΠΏΡΠΎΡΡΡΠ°Π½ΡΡΠ²Π° ΠΌΠΎΠΆΠ½ΠΎ ΡΠ·Π½Π°ΡΡ ΠΈΠ· ΠΊΠ½ΠΈΠ³ΠΈ: OβKeefe & L. Nadel, The Hippocampus as a Cognitive Map (Oxford: Clarendon Press, 1978), ΠΏΡΠΈΠ²Π΅Π΄Π΅Π½Π½Π°Ρ ΡΠΈΡΠ°ΡΠ° β ΡΡΡ. 5.
Π Π²Π½ΠΈΠΌΠ°Π½ΠΈΠΈ ΡΠΌ.: W. James, The Works of William James. The Principles of Psychology, ed. F. Burkhardt & F. Bowers, 3 vols. (1890) (reprint, Cambridge, Mass.: Harvard University Press, 1981), ΡΠΈΡΠ°ΡΠ° β ΡΠΎΠΌ 1, ΡΡΡ. 380β381 (ΠΊΡΡΡΠΈΠ² Π°Π²ΡΠΎΡΠ°).
Π Π²Π½ΠΈΠΌΠ°Π½ΠΈΠΈ, ΠΏΡΠΎΡΡΡΠ°Π½ΡΡΠ²Π΅ ΠΈ ΠΏΠ°ΠΌΡΡΠΈ ΡΠΌ.: F. A. Yates, The Art of Memory (Chicago: University of Chicago Press: London: Routledge 81 Kegan Paul, 1966).
Π ΡΠ°Π·Π»ΠΈΡΠΈΡΡ ΠΌΠ΅ΠΆΠ΄Ρ ΠΏΠΎΠ»Π°ΠΌΠΈ ΡΠΌ.: Π. A. Maguire, N. Burgess & J. OβKeefe, Human spatial navigation: Cognitive maps, sexual dimorphism and neural substrates, Current Opin. Neurobiol. 9, no. 2 (1999): 171β177.
ΠΡΡΠ³ΠΈΠ΅ ΡΠ²Π΅Π΄Π΅Π½ΠΈΡ, ΠΏΡΠΈΠ²Π΅Π΄Π΅Π½Π½ΡΠ΅ Π² ΡΡΠΎΠΉ Π³Π»Π°Π²Π΅, ΠΏΠΎΡΠ΅ΡΠΏΠ½ΡΡΡ ΠΈΠ· ΡΠ»Π΅Π΄ΡΡΡΠΈΡ ΠΈΡΡΠΎΡΠ½ΠΈΠΊΠΎΠ²: